FDA-approved drugs containing indole structures.
Compd. | Names | Activity | Targets or mechanisms |
---|---|---|---|
1 | Osimertinib | Anti-tumor | Mutant-selective EGFR inhibitor |
2 | VCR | Anti-tumor | Tubulin inhibitor |
3 | Reserpine | Anti-hypertensive | Blocking the transmission of sympathetic impulses |
4 | Tadalafil | Anti-pulmonary hypertension | Phosphodiesterase inhibitor |
5 | Fluvastatin | Hypolipidemic | Inhibition of endogenous cholesterol synthesis |
6 | Indomethacin | Anti-inflammatory | Cyclooxygenase inhibitor |
7 | Zafirlukast | Anti-asthma | Leukotriene receptor antagonist |
8 | Delavirdine | Anti-HIV | Reverse transcriptase inhibitor |