Table 3.

Summary of procedure related AEs by study arm

MedDRA system organ class (preferred term)	Arm 1 (BMAC bone marrow harvest) (N = 139)		Arm 2 (SVF fat harvest) (N = 145)		Arm 3 (UCT CSI no harvest) (N = 156)
	n (%)	95% CI	n (%)	95% CI	n (%)	95% CI
Injury, poisoning and procedural complications
Post-procedural contusion	17 (12.2)	7.3, 18.9	56 (38.6)	30.7, 47.1	0	0.0, 2.3
Post-procedural hematoma	4 (2.9)	0.8, 7.2	18 (12.4)	7.5, 18.9	0	0.0, 2.3
Procedural pain	41 (29.5)	22.1, 37.8	49 (33.8)	26.2, 42.1	1 (0.6)	0.0, 3.5

The safety population is defined as the 440 subjects who received study treatment. The AEs are those with an incidence of at least 5%. MedDRA denotes Medical Dictionary for Regulatory Activities, version 21.1.

95% CIs that do not overlap are statistically significant.