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. 2023 Nov 13;29(12):3127–3136. doi: 10.1038/s41591-023-02635-7

Extended Data Fig. 2. QTcF prolongation in healthy volunteer MAD cohort 3 (MAD3; 100 mg) and in open-label HS/AD patient cohort.

Extended Data Fig. 2

Mean change from baseline (ΔQTcF) and absolute QTcF values are shown at the indicated time points for MAD3 (100 mg daily fasted x 14 days, n = 9) and open-label patient cohort (75 mg daily fed x 28 days, n = 20). AD = atopic dermatitis; CI = confidence interval; HS = hidradenitis suppurativa; MAD = multiple ascending doses; QTcF = corrected QT interval by Fredericia.

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