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Proposed mechanism of heat shock-provoked disassembly of the λ replication complex in bacteria harboring λcro+ plasmid (A) and of heat shock resistance of the λ replication complex in bacteria harboring λcrots plasmid (B). In the case of a λcro-null plasmid, the λ replication complex should also interact with other DNA-bound proteins before temperature upshift. See the text for details.
