Table 2.
Associations between clinicopathological factors and diagnosis of anal fistula at follow-up, univariate analysis
| Characteristics | n/N | % | ORa | 95% CIb | p |
|---|---|---|---|---|---|
| Gender | |||||
| Male | 104/322 | 32.3 | 1.00 | ||
| Female | 60/153 | 39.2 | 1.31 | 0.86–2.02 | 0.202 |
| Age per 10 years | 1.00 | 0.99–1.02 | 0.453 | ||
| Smoking | |||||
| Never | 68/163 | 41.7 | 1.00 | ||
| Former | 31/83 | 37.3 | 1.09 | 0.62–1.92 | 0.755 |
| Active | 48/166 | 28.9 | 0.71 | 0.43–1.17 | 0.178 |
| Unknown | 17/63 | 27.0 | 0.64 | 0.31–1.23 | 0.191 |
| Diabetes | |||||
| No | 155/431 | 36.0 | 1.00 | ||
| Type I | 0/7 | 0 | NA | NA | |
| Type II | 9/36 | 25.0 | 0.57 | 0.22–1.27 | 0.197 |
| Body mass index | |||||
| ≤ 20 | 9/33 | 27.3 | 1.00 | ||
| > 20–25 | 50/161 | 31.1 | 1.66 | 0.67–4.73 | 0.301 |
| > 25–30 | 62/141 | 44.0 | 2.46 | 0.99–7.03 | 0.067 |
| > 30 | 40/114 | 35.1 | 1.86 | 0.73–5.40 | 0.214 |
| Perioperative EAUS | |||||
| No | 90/350 | 25.7 | 1.00 | ||
| Yes | 70/137 | 51.1 | 2.76 | 1.78–4.29 | < 0.001 |
| Inflammatory bowel disease | |||||
| No | 141/458 | 30.8 | 1.00 | ||
| Yes | 23/29 | 79.3 | 5.96 | 2.33–17.2 | < 0.001 |
| Leucocyte count, 109/L | |||||
| > 3–9 | 38/105 | 36.2 | 1.00 | ||
| > 9–12 | 42/139 | 30.2 | 0.69 | 0.39–1.23 | 0.208 |
| > 12 | 67/187 | 35.8 | 0.93 | 0.55–1.58 | 0.778 |
| C-reactive protein, mg/L | |||||
| ≤ 10 | 26/81 | 32.1 | 1.00 | ||
| > 10–50 | 56/201 | 27.9 | 0.99 | 0.55–1.85 | 0.981 |
| > 50–100 | 31/82 | 37.8 | 1.50 | 0.75–3.04 | 0.255 |
| > 100 | 33/64 | 51.6 | 3.21 | 1.57–6.71 | 0.002 |
| Abscess localisation | |||||
| Perianal | 70/283 | 24.7 | 1.00 | ||
| Low int | 27/61 | 44.3 | 3.45 | 2.01–5.93 | < 0.001 |
| High int | 7/19 | 36.8 | 1.96 | 0.66–5.30 | 0.198 |
| Ischioanal | 28/69 | 40.6 | 2.61 | 1.46–4.67 | 0.001 |
| Supralevator | 3/5 | 60.0 | 5.88 | 0.95–45.5 | 0.056 |
| Not specified | 6/14 | 42.9 | 4.90 | 1.26–2.04 | 0.021 |
| History of recurrent abscess | |||||
| No | 112/362 | 30.9 | 1.00 | ||
| Yes | 52/125 | 41.6 | 4.14 | 2.47–7.01 | < 0.001 |
| Reoperation needed | |||||
| No | 114/409 | 27.9 | 1.00 | ||
| Yes | 50/82 | 60.1 | 5.96 | 2.33–17.2 | < 0.001 |
| Microbiology, pus cultures | |||||
| No growth | 12/37 | 32.4 | 1.00 | ||
| Mixed intestinal flora | 23/60 | 38.3 | 1.65 | 0.64–4.54 | 0.312 |
| Escherichia coli | 28/48 | 58.3 | 4.06 | 1.56–11.4 | 0.005 |
| Bacteroides fragilis | 6/17 | 35.3 | 1.42 | 0.36–5.31 | 0.603 |
| Hem. Streptococcus gr. B | 1/9 | 11.1 | 0.39 | 0.02–2.64 | 0.408 |
| Staphylococcus aureus | 3/16 | 18.8 | 0.52 | 0.07–2.49 | 0.451 |
| Other | 11/36 | 30.6 | 1.04 | 0.33–3.27 | 0.943 |
aOR odds ratio
bCI confidence interval