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Dependence hierarchy of genes controlling sporulation in the aerial hyphae of S. coelicolor, adapted from reference 25 to include the whiEP1 and whiEP2 promoters. The hierarchy also shows that whiH expression is negatively regulated, directly or indirectly, by whiH itself (23). The dependence of whiH on ςWhiG is known to be direct (42).
