Table 2.
Adjusted hazard ratios of cannabis use disorder CUD on schizophrenia by sex and adjusted incidence rate ratios of CUD on schizophrenia by sex and age group
| Overall | No CUD | Males with CUD adjusted hazard ratio (95% CI) | Females with CUD adjusted hazard ratio (95% CI) | P value for the sex difference |
|---|---|---|---|---|
| 1 (ref.) | 2.42 (2.33–2.52) | 2.02 (1.89–2.17) | p < 0.001 | |
| By age group | No CUD | Males with CUD adjusted incident rate ratio (95% CI) | Females with CUD adjusted incident rate ratio (95% CI) | |
| 16–20 years | 1 (ref.) | 3.84 (3.43–4.29) | 1.81 (1.53–2.15) | p < 0.001 |
| 21–25 years | 1 (ref.) | 2.58 (2.38–2.79) | 1.91 (1.27–1.64) | p = 0.02 |
| 26–30 years | 1 (ref.) | 2.33 (2.12–2.57) | 2.08 (1.72–2.52) | p = 0.70 |
| 31–40 years | 1 (ref.) | 2.13 (1.94–2.34) | 2.31 (1.92–2.78) | p = 0.91 |
| 41+ years | 1 (ref.) | 2.18 (1.87–2.54) | 2.98 (2.32–3.84) | p = 0.16 |
Adjusted for alcohol use disorder (AUD), other substance use disorder (SUD), other psychiatric disorders, parental history of CUD, AUD, SUD, schizophrenia, or other psychiatric disorders, and whether a person was Danish-born.