Table 3. Factors Associated With Having Cardiac Testing Performed or Planned Among Adult Survivors of Childhood Cancera .
| Characteristic | Participants with testing, No./No. evaluable (%) (n = 248) | Odds ratio (95% CI)b | ||
|---|---|---|---|---|
| Factor present | Factor absent | Univariate model | Multivariable model | |
| Female sex | 45/124 (36.3) | 40/124 (32.3) | 0.83 (0.50-1.39) | NAc |
| Current age | NAd | NAd | 1.03 (1.00-1.05) | 1.03 (0.99-1.07) |
| Documentation of radiation exposure | 45/103 (43.7) | 40/145 (27.6) | 2.04 (1.19-3.47) | 0.44 (0.18-1.06) |
| Documentation of cardiotoxic chemotherapy exposure | 20/27 (74.1) | 65/221 (29.4) | 6.86 (2.77-17.00) | 1.77 (0.48-6.51) |
| Documentation of increased CV disease risk | 31/36 (86.1) | 54/212 (25.5) | 18.14 (6.71-49.01) | 11.94 (3.37-42.31) |
| Survivorship care plan noted | 11/14 (78.6) | 74/234 (31.6) | 7.93 (2.15-29.26) | 3.96 (0.58-27.18) |
| Documentation of a cancer-related late-effects surveillance or follow–up plan | 51/95 (53.7) | 34/153 (22.2) | 4.06 (2.33-7.07) | 3.92 (1.69-9.11) |
| Existing CV risk factors, No.e | NAd | NAd | 2.10 (1.49-2.95) | 2.09 (1.32-3.31) |
| Cardiology visit during preceding 2 y | 11/12 (91.7) | 74/236 (31.4) | 27.47 (3.49-216.37) | 8.29 (0.90-79.32) |
| >3 PCP visits at baselinef | 52/116 (44.8) | 33/132 (25.0) | 3.00 (1.77-5.11) | 1.78 (0.87-3.65) |
Abbreviations: CV, cardiovascular; NA, not applicable; PCP, primary care practitioner.
a
Cardiac testing was defined as electrocardiogram, echocardiogram, or other cardiac imaging.
b
Participants with missing variables were excluded from the regression model.
c
Sex was not significant in univariate testing (P = .49) and therefore was excluded from the multivariable model.
d
NA with nonbinary covariate.
e
Diagnosis of hypertension, dyslipidemia, or diabetes at baseline, modeled ordinally as 0, 1, and 2 or more conditions.
f
Based on median of 3 visits.