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. 2023 Dec 7;103:18428. doi: 10.2340/actadv.v103.18428

Table III.

Frequency of contact allergy to the Swedish baseline series and hydroperoxides of limonene and linalool in 26 conscripts with foot dermatitis compared with consecutively tested dermatitis patients (control group)

Test substances Conc. Conscripts Control group p-valuec
Testeda n Positive testb n (%) Tested n Positive test n (%)
Potassium dichromate 0.5% pet 26 0 225 3 (1.3) 1.0
p-Phenylenediamine 1.0% pet 26 0 225 3 (1.3) 1.0
Thiuram mix 1.0% pet 26 0 228 5 (2.2) 1.0
Neomycin sulphate 20.0% pet 26 0 227 1 (0.4) 1.0
Cobalt(II)chloride hexahydrate 1.0% pet 26 0 225d 7 (3.1) 1.0
Quaternium-15 1.0% pet 26 0 228 3 (1.3) 1.0
Nickel(II)sulphate hexahydrate 5.0% pet 26 1 (3.8) 225 31 (13.8) 0.21
Quinoline mix 6.0% pet 26 0 209 0
Colophonium 20.0% pet 26 13 (50) 228 1 (0.4) < 0.001
Paraben mix 16.0% pet 26 0 227 0
Black rubber mix 0.6% pet 26 0 227 2 (0.9) 1.0
Sesquiterpene lactone mix 0.1% pet 26 0 227 0
Mercapto Mix 3.5% pet 26 0 227e 1 (0.4) 1.0
Epoxy resin, Bisphenol A 1.0% pet 26 0 226 1 (0.4) 1.0
Peru balsam 25.0% pet 26 1 (3.8) 226 5 (2.2) 0.48
4-tert-Butylphenolformaldehyde resin 1.0% pet 26 1 (3.8) 227 1 (0.4) 0.19
Fragrance mix II 14.0% pet 26 2 (7.7) 227 3 (1.3) 0.084
Formaldehyde 2.0% aq 26 1 (3.8) 227 7 (3.1) 0.58
Fragrance mix I 8.0% pet 26 2 (7.7) 227 7 (3.1) 0.23
Phenol formaldehyde resin (PFR2) 1.0% pet 26 3 (11.5) 227 2 (0.9) 0.008
Diazolidinyl urea 2.0% pet 26 0 227 0
MI-MCI 0.215% aq 26 0 227f 14 (6.2) 0.37
Amerchol L-101 50.0% pet 26 0 227 1 (0.4) 1.0
Caine mix II 10.0% pet 26 0 227 1 (0.4) 1.0
Lichen acid mix 0.3% pet 26 0 227 0
Tixocortol-21-pivalate 0.1% pet 26 0 227 1 (0.4) 1.0
Textile dye mix 6.6% pet 26 0 153g 2 (1.3) 1.0
Budesonide 0.01% pet 26 0 226 0
Methyldibromo glutaronitrile 0.5% pet 26 0 227 4 (1.8) 1.0
Hydroperoxides of linalool 1% pet 26 6 (23) 208 9 (4.3) 0.003
Hydroperoxides of limonene 0.3% pet 26 9 (35) 209 10 (4.8) < 0.001

The conscripts were patch-tested in 2022. The control group consisted of consecutively tested dermatitis patients aged 20–21 years investigated in the preceding 10 years (2012 to 2021). The data are based on the results at patch-test reading day 3 or 4.

a

Total number tested;

b

total number with positive patch test;

c

Fisher’s exact test;

d

Test concentration changed during the study period: 213 were tested with cobalt(II)chloride hexahydrate 0.5%, and 12 with cobalt(II)chloride hexahydrate 1.0%;

e

Test concentration changed during the study period: 215 were tested with mercapto-mix 2.0%, and 12 with mercapto mix 3.5%;

f

test concentration changed during the study period: 52 were tested with MI-MCI 0.02%, 163 with MI-MCI 0.02% + MI 0.20%, and 12 with MI-MCI 0.215%;

g

textile dye mix was included in the baseline series from 2015.

Aq: aqua; conc.: concentration; MI-MCI: methylisothiazolinone–methylchloroisothiazolinone; pet: petrolatum. Bold figures indicate statistically significant results (< 0.05).