Table III.
Test substances | Conc. | Conscripts | Control group | p-valuec | ||
---|---|---|---|---|---|---|
Testeda n | Positive testb n (%) | Tested n | Positive test n (%) | |||
Potassium dichromate | 0.5% pet | 26 | 0 | 225 | 3 (1.3) | 1.0 |
p-Phenylenediamine | 1.0% pet | 26 | 0 | 225 | 3 (1.3) | 1.0 |
Thiuram mix | 1.0% pet | 26 | 0 | 228 | 5 (2.2) | 1.0 |
Neomycin sulphate | 20.0% pet | 26 | 0 | 227 | 1 (0.4) | 1.0 |
Cobalt(II)chloride hexahydrate | 1.0% pet | 26 | 0 | 225d | 7 (3.1) | 1.0 |
Quaternium-15 | 1.0% pet | 26 | 0 | 228 | 3 (1.3) | 1.0 |
Nickel(II)sulphate hexahydrate | 5.0% pet | 26 | 1 (3.8) | 225 | 31 (13.8) | 0.21 |
Quinoline mix | 6.0% pet | 26 | 0 | 209 | 0 | |
Colophonium | 20.0% pet | 26 | 13 (50) | 228 | 1 (0.4) | < 0.001 |
Paraben mix | 16.0% pet | 26 | 0 | 227 | 0 | |
Black rubber mix | 0.6% pet | 26 | 0 | 227 | 2 (0.9) | 1.0 |
Sesquiterpene lactone mix | 0.1% pet | 26 | 0 | 227 | 0 | |
Mercapto Mix | 3.5% pet | 26 | 0 | 227e | 1 (0.4) | 1.0 |
Epoxy resin, Bisphenol A | 1.0% pet | 26 | 0 | 226 | 1 (0.4) | 1.0 |
Peru balsam | 25.0% pet | 26 | 1 (3.8) | 226 | 5 (2.2) | 0.48 |
4-tert-Butylphenolformaldehyde resin | 1.0% pet | 26 | 1 (3.8) | 227 | 1 (0.4) | 0.19 |
Fragrance mix II | 14.0% pet | 26 | 2 (7.7) | 227 | 3 (1.3) | 0.084 |
Formaldehyde | 2.0% aq | 26 | 1 (3.8) | 227 | 7 (3.1) | 0.58 |
Fragrance mix I | 8.0% pet | 26 | 2 (7.7) | 227 | 7 (3.1) | 0.23 |
Phenol formaldehyde resin (PFR2) | 1.0% pet | 26 | 3 (11.5) | 227 | 2 (0.9) | 0.008 |
Diazolidinyl urea | 2.0% pet | 26 | 0 | 227 | 0 | |
MI-MCI | 0.215% aq | 26 | 0 | 227f | 14 (6.2) | 0.37 |
Amerchol L-101 | 50.0% pet | 26 | 0 | 227 | 1 (0.4) | 1.0 |
Caine mix II | 10.0% pet | 26 | 0 | 227 | 1 (0.4) | 1.0 |
Lichen acid mix | 0.3% pet | 26 | 0 | 227 | 0 | |
Tixocortol-21-pivalate | 0.1% pet | 26 | 0 | 227 | 1 (0.4) | 1.0 |
Textile dye mix | 6.6% pet | 26 | 0 | 153g | 2 (1.3) | 1.0 |
Budesonide | 0.01% pet | 26 | 0 | 226 | 0 | |
Methyldibromo glutaronitrile | 0.5% pet | 26 | 0 | 227 | 4 (1.8) | 1.0 |
Hydroperoxides of linalool | 1% pet | 26 | 6 (23) | 208 | 9 (4.3) | 0.003 |
Hydroperoxides of limonene | 0.3% pet | 26 | 9 (35) | 209 | 10 (4.8) | < 0.001 |
The conscripts were patch-tested in 2022. The control group consisted of consecutively tested dermatitis patients aged 20–21 years investigated in the preceding 10 years (2012 to 2021). The data are based on the results at patch-test reading day 3 or 4.
Total number tested;
total number with positive patch test;
Fisher’s exact test;
Test concentration changed during the study period: 213 were tested with cobalt(II)chloride hexahydrate 0.5%, and 12 with cobalt(II)chloride hexahydrate 1.0%;
Test concentration changed during the study period: 215 were tested with mercapto-mix 2.0%, and 12 with mercapto mix 3.5%;
test concentration changed during the study period: 52 were tested with MI-MCI 0.02%, 163 with MI-MCI 0.02% + MI 0.20%, and 12 with MI-MCI 0.215%;
textile dye mix was included in the baseline series from 2015.
Aq: aqua; conc.: concentration; MI-MCI: methylisothiazolinone–methylchloroisothiazolinone; pet: petrolatum. Bold figures indicate statistically significant results (< 0.05).