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Noradrenergic fibers stained for dopamine beta-hydroxylase are show in the region of injection in the medial, frontal cortex for an NE-LX rat (left side) and SHAM-LX rat. The mean percentage of fiber loss in this region was 56% in NE-LX rats relative to SHAM-LX rats. There was no significant loss in the adjacent cingulate cortex or the orbitofrontal cortex
