. 2023 Nov 27;8(49):46922–46933. doi: 10.1021/acsomega.3c06700

Table 3. IC₅₀ Values of VEGFR2 Kinase Activities of the Tested Compounds.

compound	PIM-1 kinase
	% of kinase inhibition	IC₅₀ [nM] ± SD^a
6	94.3 ± 1.3	19.4 ± 0.7
11	90.1 ± 2.7	42.3 ± 1.1
12	97.5 ± 1.3	14.3 ± 0.6
13	94.9 ± 2.9	19.8 ± 1.1
staurosporine	96.8 ± 2.1	16.7

Values are expressed as the average of three independent replicates. “IC₅₀ values were calculated using the sigmoidal non-linear regression curve fit of percentage inhibition against five concentrations of each compound”.

Table 3. IC50 Values of VEGFR2 Kinase Activities of the Tested Compounds.

Table 3. IC₅₀ Values of VEGFR2 Kinase Activities of the Tested Compounds.