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. 2023 Dec 1;8(49):47239–47253. doi: 10.1021/acsomega.3c07434

Table 1. IC50 Values for Evaluated Molecules Employing Doxorubicin as a Standard Druga.

    IC50 values (μM)
entry compound HepG2 MCF7 A549 MCF-10A
1 1 33.87 ± 3.34 39.76 ± 3.35 36.27 ± 3.37 NT
2 2 27.33 ± 3.87 29.39 ± 2.35 29.87 ± 3.05 NT
3 3 2.02 ± 0.15 1.61 ± 0.12 1.87 ± 0.32 77.29 ± 3.22
4 4a 13.74 ± 3.81 14.27 ± 2.05 14.87 ± 3.12 60.12 ± 2.31
5 4b 17.82 ± 2.04 18.76 ± 3.19 17.11 ± 3.17 58.12 ± 2.34
6 6 15.39 ± 3.12 15.21 ± 2.16 15.57 ± 2.94 57.02 ± 1.28
7 7 6.26 ± 0.32 5.60 ± 1.12 7.28 ± 1.34 78.54 ± 2.05
8 11 50.48 ± 3.16 60.10 ± 3.45 50.67 ± 3.23 NT
9 13 19.26 ± 2.07 18.09 ± 2.05 19.15 ± 3.88 51.57 ± 1.98
10 14 37.22 ± 1.45 39.33 ± 3.12 40.39 ± 3.15 NT
11 15 19.27 ± 2.06 19.27 ± 3.37 18.99 ± 3.45 52.33 ± 2.18
12 17 25.29 ± 1.34 29.02 ± 2.38 24.28 ± 3.88 NT
13 18 39.67 ± 1.22 45.62 ± 3.28 45.97 ± 3.65 NT
14 19 13.33 ± 1.96 15.21 ± 1.65 14.33 ± 1.96 60.45 ± 1.94
15 doxorubicin 2.71 ± 0.12 1.68 ± 0.11 2.22 ± 0.22 87.34 ± 1.47
a

The percentage inhibition (IC50) was determined from three successive tests utilizing an MTT procedure after 72 h of treatment. The statistics are reported as the mean standard deviation (S.D.). A standard drug is Doxorubicin. NT = Not Tested.