FIG. 1.

Alignment of putative extended −10 promoters of mycobacteria. Fifty-nine mycobacterial promoters for which the TSP had been experimentally determined were analyzed. The sequences of the 13 promoters which contained the TGN motif are shown. (A) Promoters from our mycobacterial promoter library. S5, S6, S16, S19, S21, and S119 are from M. smegmatis, and T101 and T129 are from M. tuberculosis. (B) rpsL gene promoter from M. smegmatis, hsp60 P2 promoter from M. bovis, repA promoter from the plasmid pAL5000 of M. fortuitum, and promoters of the 18-kDa gene and the rRNA operon of M. leprae. The extended −10 sequences are underlined.