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Scoring system to follow disease progression and define a humane endpoint
| Criteria | Score |
|---|---|
| Body position | |
| Elevated, normal >50% time | 0 |
| Elevated, normal <50% time | 1 |
| Continuously abnormal | 2 |
| Head position | |
| Elevated, normal >50% time | 0 |
| Elevated, normal <50% time | 1 |
| Continuously abnormal | 2 |
| Eye opening | |
| Normal | 0 |
| One eye closed, one eye open | 1 |
| Two eyes closed | 2 |
| Balance | |
| Normal | 0 |
| Imbalance <50% time | 1 |
| Imbalance >50% time | 2 |
| Limb functionality | |
| Normal | 0 |
| Monoparesis | 1 |
| Hemiparesis | 2 |
