TABLE 1.
Characteristics of participants according to inflammatory bowel disease (IBD) status and subtype.
| Overall | Non‐IBD | IBD | CD | UC | |
|---|---|---|---|---|---|
| n | 492,998 | 490,044 | 2954 | 915 | 2039 |
| Age (years) | 56.53 (8.09) | 56.52 (8.09) | 57.29 (8.04) | 57.16 (8.18) | 57.35 (7.98) |
| Sex | |||||
| Female | 268,372 (54.4) | 266,896 (54.5) | 1476 (50.0) | 516 (56.4) | 960 (47.1) |
| Male | 224,626 (45.6) | 223,148 (45.5) | 1478 (50.0) | 399 (43.6) | 1079 (52.9) |
| TDI | |||||
| Low deprivation | 164,336 (33.3) | 163,480 (33.4) | 856 (29.0) | 257 (28.1) | 599 (29.4) |
| Moderate deprivation | 164,332 (33.3) | 163,387 (33.3) | 945 (32.0) | 293 (32.0) | 652 (32.0) |
| High deprivation | 164,330 (33.3) | 163,177 (33.3) | 1153 (39.0) | 365 (39.9) | 788 (38.6) |
| Ethnicity | |||||
| White | 466,786 (94.7) | 464,004 (94.7) | 2782 (94.2) | 865 (94.5) | 1917 (94.0) |
| Others | 26,212 (5.3) | 26,040 (5.3) | 172 (5.8) | 50 (5.5) | 122 (6.0) |
| Smoking status | |||||
| Current | 51,898 (10.5) | 51,465 (10.5) | 433 (14.7) | 160 (17.5) | 273 (13.4) |
| Never | 271,516 (55.1) | 270,237 (55.1) | 1279 (43.3) | 417 (45.6) | 862 (42.3) |
| Previous | 169,584 (34.4) | 168,342 (34.4) | 1242 (42.0) | 338 (36.9) | 904 (44.3) |
| Drinking | |||||
| Current | 453,732 (92.0) | 451,101 (92.1) | 2631 (89.1) | 805 (88.0) | 1826 (89.6) |
| Never | 21,727 (4.4) | 21,555 (4.4) | 172 (5.8) | 60 (6.6) | 112 (5.5) |
| Previous | 17,539 (3.6) | 17,388 (3.5) | 151 (5.1) | 50 (5.5) | 101 (5.0) |
| Education | |||||
| College and above | 158,513 (32.2) | 157,781 (32.2) | 732 (24.8) | 239 (26.1) | 493 (24.2) |
| High school and below | 334,485 (67.8) | 332,263 (67.8) | 2222 (75.2) | 676 (73.9) | 1546 (75.8) |
| Physical activity | |||||
| Low | 74,360 (15.1) | 73,877 (15.1) | 483 (16.4) | 154 (16.8) | 329 (16.1) |
| Middle | 161,349 (32.7) | 160,438 (32.7) | 911 (30.8) | 293 (32.0) | 618 (30.3) |
| High | 159,664 (32.4) | 158,761 (32.4) | 903 (30.6) | 275 (30.1) | 628 (30.8) |
| NA | 97,625 (19.8) | 96,968 (19.8) | 657 (22.2) | 193 (21.1) | 464 (22.8) |
| Metabolic status | |||||
| Healthy | 224,236 (45.5) | 223,121 (45.5) | 1115 (37.7) | 339 (37.0) | 776 (38.1) |
| Unhealthy | 197,887 (40.1) | 196,515 (40.1) | 1372 (46.4) | 420 (45.9) | 952 (46.7) |
| NA | 70,875 (14.4) | 70,408 (14.4) | 467 (15.8) | 156 (17.0) | 311 (15.3) |
| C reactive protein (mg/L) | 2.58 (4.18) | 2.57 (4.17) | 3.70 (5.65) | 4.71 (7.08) | 3.24 (4.80) |
| INFLA | −0.09 (6.05) | −0.10 (6.05) | 2.01 (6.36) | 2.78 (6.64) | 1.67 (6.20) |
| Diet score | 3.66 (1.36) | 3.66 (1.36) | 3.51 (1.39) | 3.50 (1.40) | 3.51 (1.38) |
| CCI Index | 0.27 (0.90) | 0.27 (0.90) | 0.40 (1.03) | 0.38 (0.96) | 0.41 (1.06) |
| Body mass index (kg/m2) | 27.44 (4.80) | 27.43 (4.80) | 27.95 (5.02) | 28.13 (5.30) | 27.87 (4.88) |
| Waist circumference (cm) | 90.30 (13.48) | 90.29 (13.47) | 92.44 (13.63) | 92.40 (13.80) | 92.46 (13.56) |
| Body fat percentage (%) | 31.45 (8.48) | 31.45 (8.48) | 31.58 (8.65) | 32.57 (8.82) | 31.14 (8.54) |
| Whole body fat mass (kg) | 24.86 (9.49) | 24.86 (9.49) | 25.47 (9.89) | 26.20 (10.46) | 25.14 (9.61) |
| Whole body fat‐free mass (kg) | 53.22 (11.42) | 53.22 (11.42) | 54.12 (11.58) | 52.97 (11.48) | 54.64 (11.58) |
| The ratio of waist circumference and hip circumference | 0.87 (0.09) | 0.87 (0.09) | 0.89 (0.09) | 0.88 (0.09) | 0.89 (0.09) |
| Height (cm) | 168.45 (9.28) | 168.45 (9.28) | 168.60 (9.39) | 167.69 (9.37) | 169.00 (9.38) |
| The ratio of waist circumference and height | 0.54 (0.08) | 0.54 (0.08) | 0.55 (0.08) | 0.55 (0.08) | 0.55 (0.08) |
| A body shape index (ABSI) | 0.77 (0.05) | 0.77 (0.05) | 0.77 (0.05) | 0.77 (0.05) | 0.78 (0.05) |
| Body roundness index (BRI) | 4.17 (1.59) | 4.17 (1.59) | 4.43 (1.67) | 4.50 (1.73) | 4.40 (1.64) |
Note: The continuous and categorical variables were described as mean (SD) and proportion (%).
Abbreviations: CCI, Charlson comorbidity index; CD, Crohn'’s diseases; IBD, inflammatory bowel diseases; SD, standard deviation; TDI, Townsend deprivation index; UC, ulcerative colitis.