Table 1.

Eligibility criteria using PICOS population, interventions, comparators, outcomes, and study design.

PICOS	Description
Participant	Anti-QSA against clinically relevant pathogens
Intervention	Evaluation approaches and methodologies for developing anti-QSA
Comparators	Antibiotic that directly kills or inhibits bacteria
Outcomes	Anti-QSA for treating infections avoiding bacterial resistance reducing damage to normal flora and host tissue enhancing host immune system
Study design	Systematic reviews including quantitative and qualitative studies