TABLE 2.

Selected biomarker candidates.

Gene name	PCa vs normal tissues		PreOp vs PostOp plasma		PreOp vs PostOp urine		Published data supporting biomarker validity
	Log2FC	adj. p-value	Log2FC	adj. p-value	Log2FC	adj. p-value
mRNA
GLO1	1.47	3.16 × 10−13	0	0	4.07	3.98 × 10−3	Rounds et al. (2021)
NKX3-1	2.76	4.67 × 10−5	0.76	0.97	2.67	0.012	Huang et al. (2018)
AMD1	2.00	2.78 × 10−22	−0.55	0.97	3.97	1.11 × 10−3	Bajo-Santos et al. (2023)
PMEPA1	2.85	5.35 × 10−16	−0.42	0.97	2.72	2.03 × 10−3	Sharad et al. (2020)
RBM47	2.74	1.36 × 10−8	1.37	0.97	2.48	9.17 × 10−3	Bajo-Santos et al. (2023)
MAZ	3.37	1.63 × 10−20	2.75	0.97	3.54	1.3 × 10−4	Bajo-Santos et al. (2023)
lncRNA
PCA3	9.08	1.32 × 10−85	−0.24	0.96	1.88	0.36	Woo et al. (2019)
PCAT14	7.17	129 × 10−32	0	0	2.45	0.34	Yan et al. (2021)
tRFs
tRF-Phe-GAA-3b	−0.59	0.92	−2.00	0.43	1.19	0.62	Olvedy et al. (2016)
tRF-Lys-CTT-5c	−0.08	0.92	1.4	0.43	0.94	0.62	Olvedy et al. (2016)
miRNAs
miR-375-3p	2.90	1.51 × 10−4	1.01	0.99	1.45	3.22 × 10−3	Foj et al. (2017)
miR-92a -1-5p	1.73	7.95 × 10−4	0.68	0.99	1.90	3.22 × 10−3	Mercadal et al. (2020)
miR-27a - 5p	1.06	2.80 × 10−4	−0.54	0.99	0.63	0.62	Ku et al. (2021)
miR-196a-5p	1.13	6.51 × 10−5	0.27	0.99	0.57	0.56	Rodríguez et al. (2017)
piRNA
piR-28004	12.30	0	−4.88	0.23	6.47	1.77 × 10−3	Bajo-Santos et al. (2023)