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. 2023 Aug 30;14(6):1479–1498. doi: 10.1016/j.advnut.2023.08.012

TABLE 1.

PICO for study inclusion

Participants (P) Intervention (I) Comparison (C) Outcomes (O)
Inclusion criteria
 Participants ≥18 y Vitamin D supplementation in the form of vitamin D3 (cholecalciferol) or vitamin D2 (ergocalciferol) at any dose, given orally, daily, weekly, or monthly. RCTs with the intervention compared to placebo Triglyceride levels (mg/dL), Total cholesterol levels (mg/dL), LDL-C (mg/dL), and HDL- C (mg/dL)
Exclusion criteria
 Participants <18 y Vitamin D supplements with other vitamin and chemical element supplements; vitamin D supplementation in fortified foods as the amount of vitamin cannot be defined accurately.

Abbreviations: RCT, randomized controlled trial.