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. 2023 Nov 17;12(11):1459–1474. doi: 10.21037/gs-23-226

Table 2. The characteristics of patient with low SIRI versus high SIRI in the cohort.

Characteristics Low SIRI, n (%) High SIRI, n (%) P value
Age 0.072
   ≤50 years 141 (80.6) 34 (19.4)
   >50 years 76 (89.4) 9 (10.6)
Menopausal 1.000
   Premenopausal 132 (75.0) 44 (25.0)
   Postmenopausal 63 (75.0) 21 (25.0)
Pre-NACT T stage 0.506
   T1–2 123 (84.8) 22 (15.2)
   T3–4 94 (81.7) 21 (18.3)
Pre-NACT N stage 0.126
   N0–1 71 (88.8) 9 (11.2)
   N2–3 146 (81.1) 34 (18.9)
Pre-NACT TNM stage 0.167
   IA–IIB 51 (89.5) 6 (10.5)
   IIIA–IIIC 166 (81.8) 37 (18.2)
Tumor grade 0.028
   I–II 88 (89.8) 10 (10.2)
   III 55 (77.5) 16 (22.5)
LVI 0.054
   No 121 (79.6) 31 (20.4)
   Yes 82 (89.1) 10 (10.9)
Pathological N stage 0.081
   N0–1 142 (80.7) 34 (19.3)
   N2–3 75 (89.3) 9 (10.7)
ER 0.005
   Negative 72 (75.0) 24 (25.0)
   Positive 145 (88.4) 19 (11.6)
PR 0.006
   Negative 97 (77.0) 29 (23.0)
   Positive 120 (89.6) 14 (10.4)
HER2 0.579
   Negative 126 (84.6) 23 (15.4)
   Positive 91 (82.0) 20 (18.0)
Molecular subtype 0.023
   Luminal A 61 (85.9) 10 (14.1)
   Luminal B 90 (90.0) 10 (10.0)
   HER2 positive 35 (71.4) 14 (28.6)
   TNBC 31 (77.5) 9 (22.5)
AR 0.10
   Negative 13 (72.2) 5 (27.8)
   Positive 116 (89.2) 14 (10.8)
Ki-67 0.10
   ≥30% 110 (80.3) 27 (19.7)
   <30% 102 (87.9) 14 (12.1)
pCR 0.772
   No 162 (83.1) 33 (16.9)
   Yes 55 (84.6) 10 (15.4)

SIRI, systemic inflammation response index; pre-NACT, pre-neoadjuvant chemotherapy; TNM, tumor-node-metastasis; LVI, lymph vascular invasion; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; TNBC, triple negative breast cancer; AR, androgen receptor; pCR, pathological complete response.