Table 5. The multivariate Cox regression analysis of SIRI change for DFS.
| Characteristics | Multivariate analysis | ||
|---|---|---|---|
| HR | 95% CI | P value | |
| Pre-NACT T stage (T1–2 vs. T3–4) | 0.774 | 0.47–1.24 | 0.294 |
| Pre-NACT N stage (N0–1 vs. N2–3) | 0.609 | 0.33–1.11 | 0.106 |
| Ki-67 (<30% vs. ≥30%) | 0.546 | 0.33–0.89 | 0.016 |
| pCR (no vs. yes) | 2.360 | 1.18–4.70 | 0.015 |
| SIRI change after NACT (major vs. minor) | 1.721 | 1.03–2.86 | 0.037 |
SIRI, systemic inflammatory response index; DFS, disease free survival; HR, hazard ratio; CI, confidence interval; pre-NACT, pre-neoadjuvant chemotherapy; pCR, pathological complete response.