Table 2. The cardiovascular parameters of CTPA in patients with chronic thromboembolic pulmonary hypertension (mPAP >20 mmHg) and without pulmonary hypertension (mPAP ≤20 mmHg) according to the 2022 ESC/ERS guidelines.
| Variable | Interobserver agreement(ICC, N=180) | Group without PH, mPAP ≤20 mmHg (N=50) | CTEPH group, mPAP >20 mmHg (N=130) |
P value |
|---|---|---|---|---|
| Cobb angle (degree) | 0.970 | 36.7±8.1 | 54.2±13.4 | <0.001** |
| MPAd (mm) | 0.961 | 26.7±3.5 | 35.6±5.4 | <0.001** |
| AAd (mm) | 0.960 | 32.8±5.3 | 32.2±4.8 | 0.447 |
| RVtd (mm) | 0.963 | 35.8±4.0 | 47.7±9.7 | <0.001** |
| RVld (mm) | 0.974 | 67.2±10.4 | 75.0±9.5 | <0.001** |
| RAtd (mm) | 0.912 | 43.3±6.4 | 54.9±11.7 | <0.001** |
| RAld (mm) | 0.904 | 39.4±8.0 | 50.4±11.6 | <0.001** |
| LVtd (mm) | 0.974 | 39.4±6.9 | 36.0±8.0 | 0.009* |
| LVld (mm) | 0.929 | 70.0±8.9 | 67.4±9.7 | 0.096 |
| LAlr (mm) | 0.870 | 55.2±8.4 | 56.3±9.2 | 0.462 |
| LAap (mm) | 0.874 | 39.2±7.3 | 39.0±7.0 | 0.90 |
| RVa (mm2) | 0.957 | 18.7±5.3 | 29.0±9.3 | <0.001** |
| RAa (mm2) | 0.947 | 15.0±4.7 | 24.4±10.5 | <0.001** |
| LVa (mm2) | 0.961 | 24.2±6.5 | 21.6±6.8 | 0.029* |
| LAa (mm2) | 0.928 | 17.5±4.9 | 16.6±5.3 | 0.172 |
| RVWT (mm) | 0.818 | 3.1±1.1 | 5.5±1.6 | <0.001** |
| IVST (mm) | 0.942 | 9.9±2.1 | 9.2±2.1 | 0.056 |
| MPAd/AAd ratio | 0.971 | 0.83±0.15 | 1.13±0.24 | <0.001** |
| RVtd/LVtd ratio | 0.974 | 0.93±0.14 | 1.41±0.50 | <0.001** |
| RVa/LVa ratio | 0.977 | 0.79±0.16 | 1.5±0.80 | <0.001** |
| RVWT/IVST ratio | 0.866 | 0.32±0.11 | 0.63±0.22 | <0.001** |
Continuous variables are expressed as mean value ± standard deviation. *, P<0.05 and **, P<0.001 are considered statistically significant. CTPA, computed tomography pulmonary angiography; mPAP, mean pulmonary arterial pressure; ESC, European Society of Cardiology; ERS, European Respiratory Society; ICC, intraclass correlation coefficient; PH, pulmonary hypertension; CTEPH, chronic thromboembolic pulmonary hypertension; MPAd, diameter of the main pulmonary artery; AAd, diameter of the ascending aorta; RVtd, transverse diameter of the right ventricle; RVld, longitudinal diameter of the right ventricle; RAtd, transverse diameter of the right atrium; RAld, longitudinal diameter of the right atrium; LVtd, transverse diameter of the left ventricle; LVld, longitudinal diameter of the left ventricle; LAlr, left-right diameter of the left atrium; LAap, anteroposterior diameter of the left atrium; RVa, area of the right ventricle; RAa, area of the right atrium; LVa, area of the left ventricle; LAa, area of the left atrium; RVWT, right ventricular free wall thickness; IVST, interventricular septal thickness.