Table 4.

The association of SNP-based groups with OS on the basis of a multivariable Cox model.

	Overall survival
	N = 878, events = 91
Variable	HR (95% CI)	P value
SNP-based groups
0 high-risk SNP	1
1 high-risk SNP	2.42 (1.04–5.70)	0.040
>1 high-risk SNP	3.00 (1.24–7.32)	0.015
Tumor size
pT1	1
pT2	1.59 (0.99–2.59)	0.057
pT3–4	2.92 (1.55–5.51)	<0.001
Nodal status
pN0	1
pN+	2.16 (1.24–3.76)	0.007
(Neo)adjuvant chemotherapy
No	1
Yes	0.87 (0.45–1.66)	0.667
Age at diagnosis	1.06 (1.03–1.09)	<0.001
Study cohort
GIM4	1
GIM5	0.78 (0.46–1.28)	0.325