Skip to main content
. 2023 Dec 1;14:1285943. doi: 10.3389/fimmu.2023.1285943

Figure 1.

Figure 1

Representation of the experimental design. BALB/c mice were divided into three groups and they were i.p. administrated with PBS three times per week (control group), 20 mg/kg anti-TNF twice per week or 2.5 mg/kg MTX three times per week. These regiments were maintenance until the end of the experiment. One week after (W0) mice were intravenously infected with L. infantum promastigotes. Six weeks post-infection, animals were i.p. treated with 20 mg/kg Glucantime® per day for 21 days (W9).