Table 3.
Prognostic factors for overall survival.
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR(95% CI) | P | HR(95% CI) | P | |
| age | ||||
| <65 | [reference] | [reference] | ||
| ≥65 | 1.472(1.194-1.815) | <0.001 | 1.241(0.995-1.548) | 0.055 |
| Gender | ||||
| Male | [reference] | |||
| Female | 0.908(0.721-1.144) | 0.414 | ||
| Race | ||||
| White | [reference] | |||
| Black | 0.880(0.683-1.136) | 0.327 | ||
| American indian/Alska native | 1.438(0.592-3.493) | 0.422 | ||
| Asian or Pacific Islander | 0.798(0.591-1.080) | 0.144 | ||
| Unknown | NA | NA | ||
| Marital status | ||||
| Married | [reference] | |||
| Single | 0.881(0.663-1.172) | 0.386 | ||
| Divorced/Widowed/Separated | 1.100(0.824-1.467) | 0.517 | ||
| Unknown | 1.133(0.691 -1.857) | 0.620 | ||
| Surgery | ||||
| NO | [reference] | [reference] | ||
| YES | 0.446(0.359 -0.555) | <0.001 | 0.416(0.330-0.525) | <0.001 |
| Primary site | ||||
| Gastric antrum | [reference] | [reference] | ||
| Cardia and fundus of stomach | 0.799(0.599-1.066) | 0.128 | 1.031(0.764-1.391) | 0.840 |
| Body of stomach | 0.572(0.335- 0.976) | <0.05 | 0.761(0.436-1.328) | 0.336 |
| Other sites | 0.968(0.742 -1.262) | 0.810 | 1.259(0.955-1.661) | 0.102 |
| Adenocarcinoma | ||||
| YES | [reference] | [reference] | ||
| NO | 0.435(0.339 -0.557) | <0.001 | 0.523(0.395-0.693) | <0.001 |
| T | ||||
| T1 | [reference] | |||
| T2 | 0.851(0.463-1.564) | 0.605 | ||
| T3 | 0.901(0.555-1.465) | 0.676 | ||
| T4 | 1.134(0.704-1.828) | 0.604 | ||
| Unknown | 1.166(0.680-1.999) | 0.576 | ||
| N | ||||
| N0 | [reference] | [reference] | ||
| N1 | 1.677(1.268-2.218) | <0.001 | 1.149(0.853-1.547) | 0.360 |
| N2 | 1.979(1.428-2.743) | <0.001 | 1.049(0.736-1.495) | 0.789 |
| N3 | 2.404(1.729-3.342) | <0.001 | 1.313(0.912-1.888) | 0.141 |
| Unknown | 2.765(1.829-4.180) | <0.001 | 1.669(1.087 -2.562) | <0.05 |
| Grade | ||||
| I/II | [reference] | [reference] | ||
| III/IV | 1.465(1.160-1.850) | <0.01 | 1.784 (1.396-2.280) | <0.001 |
| Unknown | 0.674(0.479-0.948) | <0.05 | 1.049(0.731-1.505) | 0.795 |
| Radiation | ||||
| No | [reference] | |||
| Yes | 1.061(0.784-1.437) | 0.7 | ||
| Chemotherapy | ||||
| No | [reference] | [reference] | ||
| Yes | 0.490(0.395-0.609) | <0.001 | 0.409(0.323-0.517) | <0.001 |
| Synchronous metastasis patterns | ||||
| Only liver metastasis | [reference] | [reference] | ||
| Liver combined with one other site metastasis | 2.882(2.083-3.987) | <0.001 | 3.222(2.282-4.550) | <0.001 |
| Liver combined with two other site metastasis | 0.564(0.079-4.032) | 0.569 | 0.696(0.095-5.100) | 0.722 |
| Liver combined with three other site metastasis | Not available | Not available | Not available | Not available |
| Liver combined with unknown other metastasis | 1.848(1.185-2.882) | <0.01 | 1.342(0.850-2.120) | 0.206 |
Statistical significance was set at p<0.05. The bold values mean the significant difference between variables.