Table 4.
Prognostic factors for cancer-specific survival.
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| HR(95% CI) | P | HR(95% CI) | P | |
| age | ||||
| <65 | [reference] | [reference] | ||
| ≥65 | 1.346(1.083-1.673) | <0.01 | 1.145(0.910-1.442) | 0.245 |
| Gender | ||||
| Male | [reference] | |||
| Female | 0.899(0.706-1.143) | 0.386 | ||
| Race | ||||
| White | [reference] | |||
| Black | 0.852(0.653-1.112) | 0.240 | ||
| American indian/Alska native | 1.529(0.628-3.716) | 0.349 | ||
| Asian or Pacific Islander | 0.777(0.567-1.066) | 0.119 | ||
| Unknown | Not available | Not available | ||
| Marital status | ||||
| Married | [reference] | |||
| Single | 0.923(0.691-1.235) | 0.593 | ||
| Divorced/Widowed/Separated | 1.067(0.788-1.445) | 0.672 | ||
| Unknown | 1.001(0.582-1.722) | 0.996 | ||
| Surgery | ||||
| NO | [reference] | [reference] | ||
| YES | 0.436(0.348-0.546) | <0.001 | 0.417(0.328-0.530) | <0.001 |
| Primary site | ||||
| Gastric antrum | [reference] | [reference] | ||
| Cardia and fundus of stomach | 0.827(0.614-1.114) | 0.212 | 1.073(0.787-1.463) | 0.654 |
| Body of stomach | 0.545(0.308-0.963) | <0.05 | 0.748(0.414-1.353) | 0.338 |
| Other sites | 0.963(0.730-1.271) | 0.793 | 1.287(0.964-1.718) | 0.086 |
| Adenocarcinoma | ||||
| YES | [reference] | [reference] | ||
| NO | 0.427(0.329-0.554) | <0.001 | 0.504(0.376-0.677) | <0.001 |
| T stage | ||||
| T1 | [reference] | |||
| T2 | 0.786(0.408-1.514) | 0.472 | ||
| T3 | 0.946(0.567-1.578) | 0.834 | ||
| T4 | 1.183(0.715-1.957) | 0.512 | ||
| Unknown | 1.174(0.665-2.073) | 0.579 | ||
| N stage | ||||
| N0 | [reference] | [reference] | ||
| N1 | 1.769(1.324-2.363) | <0.001 | 1.200(0.881-1.635) | 0.246 |
| N2 | 1.879(1.328-2.658) | <0.001 | 0.995(0.683-1.449) | 0.979 |
| N3 | 2.535(1.805-3.559) | <0.001 | 1.358(0.934-1.976) | 0.108 |
| Unknown | 2.592(1.669-4.026) | <0.001 | 1.530(0.970-2.414) | 0.067 |
| Grade | ||||
| I/II | [reference] | [reference] | ||
| III/IV | 1.467(1.150-1.871) | <0.01 | 1.782(1.381-2.299) | <0.001 |
| Unknown | 0.689(0.484-0.982) | <0.05 | 1.085(0.746-1.578) | 0.667 |
| Radiation | ||||
| No | [reference] | |||
| Yes | 1.133(0.833-1.54) | 0.427 | ||
| Chemotherapy | ||||
| No | [reference] | [reference] | ||
| Yes | 0.512(0.408-0.643) | <0.001 | 0.421(0.330-0.539) | <0.001 |
| Synchronous metastasis patterns | ||||
| Only liver metastasis | [reference] | [reference] | ||
| Liver combined with one other site metastasis | 2.879(2.057-4.031) | <0.001 | 3.268(2.286-4.673) | <0.001 |
| Liver combined with two other site metastasis | 0.625(0.087-4.469) | 0.640 | 0.754(0.102-5.532) | 0.781 |
| Liver combined with three other site metastasis | Not available | Not available | Not available | Not available |
| Liver combined with unknown other metastasis | 1.902(1.205-3.002) | <0.01 | 1.428(0.894-2.282) | 0.135 |
Statistical significance was set at p<0.05. The bold values mean the significant difference between variables.