Table 3.
LINE-1 methylation and PTA score in SSNHL cases stratified by genotypes
|
SLC40A1 − 8CG (rs11568351) |
HAMP − 582AG (rs10421768) |
HFE C282Y c.845G > A (rs1800562) |
HFE H63D c.187C > G (rs1799945) |
TF P570S c.1765C > T (rs1049296) |
SOD2 A16V c.47C > T (rs4880) |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Cases n = 206 (%) |
CC 127 (61.6) |
CG 62 (30.1) |
GG 17 (8.2) |
AA 109 (52.9) |
AG 82 (39.8) |
GG 15 (7.3) |
GG 199 (96.6) |
GA 7 (3.4) |
CC 149 (72.3) |
CG 55 (26.7) |
GG 2 (0.97) |
CC 145 (70.3) |
CT 53 (25.7) |
TT 8 (3.9) |
CC 43 (20.9) |
CT 97 (47.1) |
TT 66 (32.0) |
|
LINE-1% mean ± SD |
87.9 ± 3.9 | 87.09 ± 3.6 | 86.0 ± 4.4 | 87.76 ± 3.5 | 87.63 ± 4.1 | 87.74 ± 3.9 | 87.5 ± 3.8 | 86.1 ± 3.6 | 86.7 ± 3.8 | 88.9 ± 3.0 | 91.5 ± 1.7 | 87.3 ± 3.9 | 87.7 ± 3.7 | 87.4 ± 3.6 | 86.6 ± 3.8 | 87.7 ± 4.0 | 87.6 ± 3.5 |
|
PTA dB mean ± SD |
59.36 ± 22.5 | 62.3 ± 23 | 68.35 ± 22.1 | 62.1 ± 22.4 | 60.45 ± 21.2 | 56.03 ± 31.5 | 61.11 ± 22.9 | 57.53 ± 20.3 | 60.99 ± 22.1 | 61.22 ± 24.4 | 54.35 ± 10.5 | 61.66 ± 22.5 | 59.38 ± 23.3 | 59.46 ± 23.1 | 61.09 ± 15.1 | 61.19 ± 25.6 | 61.36 ± 22.3 |