Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Dec 15;42:341. doi: 10.1186/s13046-023-02912-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 6 — Assessment of in vivo killing of UniCAR T-cells redirected by αFAP TMs. Female NXG mice were injected with either HT1080 hFAP Luc cells (orange), HT1080 hFAP Luc cells and UniCAR T-cells (blue), or HT1080 hFAP Luc cells and UniCAR T-cells in combination with either αFAP-scFv (black) or –IgG4 TM (grey). a the bioluminescence signals of the HT1080 hFAP cells in all groups were monitored for 10 days. b based on the luminescence imaging results obtained, a quantitative analysis was performed and are represented as mean ± SD for 5 individual mice. Statistical relevance was calculated using two-way ANOVA and Dunnett multiple-comparison test with respect to the control group injected with HT1080 hFAP Luc cells alone