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. 2023 Dec 13;19:17448069231222406. doi: 10.1177/17448069231222406

Figure 4.

Figure 4.

PKC/PKA phosphorylation of AMPA Requires AKAP. Sensory neurons cultured, transfected in mock fashion or with AKAP150 siRNA, serum-starved, then treated with PMA (1 μM, 15 min, PKC activator) or 8-Br-cAMP (10 μM, 15 min, PKA activator), and harvested for WB analysis. (a) Representative WB results, n = 4 trials. (b) Quantitative analysis of immunoreactive densitometry, means ± SEM, p-S831 PMA versus Veh ***p = .0003, p-S845 PMA versus Veh ***p = .0001, p-S880 8-Br-cAMP versus Veh **p = .009, NS = no significance, unpaired t test.