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. 2023 Dec 13;19:17448069231222406. doi: 10.1177/17448069231222406

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — AKAP Mediates AMPA GluR1/2 Surface Expression. Sensory neurons cultured, transfected in mock fashion or with AKAP150 siRNA, serum-starved, then treated with vehicle, 8-Br-cAMP (10 μM, 10 min, PKA activator) or PMA (1 μM, 10 min, PKC activator), surface biotinylated, streptavidin precipitated, and harvested for WB analysis. (a) Representative WB results, n = 4 trials, means ± SEM shown. Densitometric quantification of AMPA GluR1 biotinylation (b), ***p = .0008, GluR2 biotinylation (c) ***p = .0007, NS = no significance, unpaired t test.