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. Author manuscript; available in PMC: 2023 Dec 15.
Published in final edited form as: Science. 2021 Jun 11;372(6547):1169–1175. doi: 10.1126/science.abd8377

Fig. 4. bCSE inhibition synergizes gentamycin in murine models of infection.

Fig. 4.

(A) Acute S. aureus-induced bacteremia model. Treatment with Gm or NL1 alone did not increase survival of mice after lethal infection with S. aureus. Treatment with NL1+Gm improved survival to 50%. Study design is shown on top. (B) P. aeruginosa intranasal lung infection model. Treatment with the combination of Gm and NL1 significantly decreased bacteria burden in lungs. Graph represents the mean ± SE, *P<0.05.