Table 1.
Laboratory investigations
| Parameters | Mean values (X¯±SD) |
|||||||
|---|---|---|---|---|---|---|---|---|
| n | Baseline | n | Day 4 | n | Day 7 | n | Day 14 | |
| Neutrophils (%) | 20 | 83.46±10.20 | 20 | 83.58±7.47 | 16 | 75.62±14.77 | 09 | 77.41±14.30 |
| TLC | 20 | 13.46±07.48 | 20 | 09.73±04.12* (-03.73±07.37 (0.035) |
17 | 16.54±18.06 | 09 | 13.80±07.87 |
| Lymphocytes (%) | 20 | 12.61±16.12 | 20 | 10.49±7.13 | 17 | 14.01±10.20 | 09 | 12.13±9.27 |
| Eosinophils (%) | 20 | 0.59±16.12 | 20 | 0.12±0.21 | 17 | 0.34±0.66 | 09 | 1.13±1.46 |
| Monocytes (%) | 20 | 5.72±3.46 | 20 | 5.40±2.96 | 17 | 6.79±3.46 | 09 | 9.07±4.38 |
| Basophils (%) | 19 | 0.18±0.12 | 20 | 0.25±0.21 | 17 | 0.25±0.18 | 09 | 0.24±0.16 |
| Platelet Count (/cmm) | 20 | 185.70±104.23 | 20 | 174.11±101.47 | 17 | 195.08±121.94 | 09 | 216.56±147.43 |
| Serum total bilirubin | 11 | 1.03±0.53 | 09 | 0.80±0.55 | 09 | 0.80±0.27 | 02 | 0.75±0.64 |
| Alkaline Phosphatase | 10 | 93.61±59.34 | 10 | 330.83±749.19 | 09 | 349.78±427.31 | 02 | 115.00±104.65 |
| AST (SGOT) | 11 | 46.36±33.65 | 09 | 100.67±87.68 | 09 | 150.78±325.17 | 02 | 38.00±4.24 |
| ALT (SGPT) | 11 | 52.09±50.27 | 09 | 120.11±123.33 | 09 | 88.89±129.58 | 20 | 9.30±1.31 |
| Serum Creatinine | 20 | 1.83±1.57 | 20 | 1.60±1.35 | 18 | 1.81±1.77 | 09 | 2.44±2.14 |
| Blood Urea | 20 | 99.30±64.73 | 20 | 99.05±76.53 | 18 | 104.94±75.66 | 09 | 112.78±67.08 |
| C reactive protein | 06 | 173.88±160.01 | 01 | 62.10±0.00 | 04 | 86.05±55.10 | 00 | - |
*By Student t-test: Not Significant for all except TLC count at day 4. All laboratory parameters did not show any significant change after therapy till the end of the study except * TLC count at day 4