Table 2.
Association of various patient parameters with disease severity
| Parameter | COVID-19 Disease severity |
Total | P | ||
|---|---|---|---|---|---|
| Mild (n=31) | Moderate (n=35) | Severe (n=19) | |||
| Patients with breathlessness | 11 | 28 | 19 | 58 | <0.0001† |
| Patients without breathlessness | 20 | 7 | 0 | 27 | |
| Patients with cough | 17 | 21 | 11 | 49 | 0.914† |
| Patients without cough | 14 | 14 | 8 | 36 | |
| Patients with fatigue | 23 | 32 | 19 | 74 | 0.021* |
| Patients without fatigue | 8 | 3 | 0 | 11 | |
| Patients with chest pain | 3 | 8 | 8 | 19 | 0.036* |
| Patients without chest pain | 28 | 27 | 11 | 66 | |
| Patients with fever | 2 | 4 | 2 | 8 | 0.803* |
| Patients without fever | 29 | 31 | 17 | 77 | |
| mMRC Grade 0 | 20 | 4 | 0 | 24 | <0.0001* |
| mMRC Grade 1 | 8 | 8 | 0 | 16 | |
| mMRC Grade 2 | 3 | 17 | 9 | 29 | |
| mMRC Grade 3 | 0 | 6 | 10 | 16 | |
| Normal spirometry pattern | 27 | 19 | 0 | 46 | <0.0001* |
| Restrictive spirometry pattern | 4 | 16 | 17 | 37 | |
| Mixed spirometry pattern | 0 | 0 | 2 | 2 | |
| FEV1(%) (Mean±SD) | 111.71±22.22 | 86.66±21.39 | 63.63±18.59 | 90.65±27.77 | <0.0001‡ |
| FVC (%) (Mean±SD) | 100.94±20.17 | 79.74±20.02 | 60.89±14.49 | 83.26±24.21 | <0.0001‡ |
| FEV1/FVC (%) (Mean±SD) | 110.97±11.03 | 109.51±13 | 105.89±21.3 | 109.24±14.58 | 0.49‡ |
| Age (Mean±SD) | 58.09±12.41 | 47.96±15.28 | 54.87±14.11 | 0.004§ | |
*Fisher's exact test, †Chi-square test, ‡ANOVA, §Independent t-test. mMRC-Modified Medical Research Council. FEV1: Forced expiratory volume in one second. FVC: Forced vital capacity. SD-Standard deviation