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Fold-changes in the frequencies of cells with high cell scores in drug-treated vs. vehicle control-treated slice cultures in the myeloid cell scHPF model for A) a histone/metallothionein factor; B) a monocyte/macrophage factor; C) a macrophage factor; and D) a pro-inflammatory factor. Here, each dot represents an individual patient (i.e. biological replicates). For each drug, ** indicates FDR<0.05 based on a linear mixed model.
