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[Preprint]. 2023 Dec 10:2023.12.09.570874. [Version 1] doi: 10.1101/2023.12.09.570874

Figure 6. SIRPA and CD47 are inversely correlated, and are independently associated with platelet count in ET patients.

Figure 6.

(A) Correlation of platelet normalized gene expression between CD47 and SIRPA for patients with essential thrombocythemia and healthy donors. Closed circles navy or light blue indicate sample type respectively of healthy donors as controls (CTRL, n=11) and patients with essential thrombocythemia (ET, n=23). Inverse correlation is indicated by a dotted curve as a guide to the eye. Platelet gene expression as assessed by normalized counts of (B) SIRPA and (C) CD47 as a function of patient platelet counts (K/uL) at the time of specimen banking and platelet isolation. Closed circles navy or light blue indicate sample type respectively of healthy donors as controls (CTRL, n=11) and patients with essential thrombocythemia (ET, n=23).