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[Preprint]. 2023 Dec 5:2023.12.05.23299392. [Version 1] doi: 10.1101/2023.12.05.23299392

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Figure 2. — mtDNA-CN inversely related with age in the UKB. (A- B) The predicted mtDNA-CN residuals using the unadjusted model (including only non-linear age (restricted cubic splines with 3 knots), asthma status, and an interaction between non-linear age and asthma status) decreases with age in non-asthmatics and all asthmatics (A), and in mild asthmatics, and moderate-severe asthmatics (B). (C- D) The predicted mtDNA-CN residuals marginally adjusted for sex, center, log-transformed neutrophil and eosinophil counts, and platelet counts were significantly related with age in non-asthmatics and all asthmatics (C), and in mild asthmatics, and moderate-severe asthmatics (D).