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Odds ratios for risk of three or more exacerbations in the subsequent year for biomarkers of asthma. Cutoff values were determined (Table E5) for mtDNA-CN, serum superoxide dismutase activity, and fractional exhaled nitric oxide. A higher mtDNA-CN predicted a lower risk of three or more exacerbations, while a higher fractional exhaled nitric oxide predicted a greater risk of three or more exacerbations.
