Figure 1.

Positive detection of neutralizing antibodies in E. helvum by PVNA assay. Neutralization curves derived from pMN assays against positive samples that were selected from the initial screening, red curves denoting positive control reagents, with the exception of GH-M-74a which was not neutralized by NiV 102.4 mAb (red dotted line) (A). IC50s calculated by pMN assays against each PV (B). In the panel displaying samples positive for NiV, empty white circles denote samples that did not cross-neutralize GH-M74a. Number of samples positive for neutralizing antibodies against multiple viruses (C).