Table 5.
Univariate and Multivariate Cox Regression Analysis for Predicting Recurrence in Patients with Nonparoxysmal AF
| Parameters | Univariate Cox Regression | Multivariate Cox Regression | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | 0.991 (0.973–1.009) | 0.310 | ||
| Female sex | 1.410 (0.974–2.042) | 0.069 | 1.536 (1.030–2.292) | 0.035 |
| BMI | 1.062 (1.006–1.122) | 0.031 | 1.054 (0.996–1.116) | 0.071 |
| AF duration | 1.002 (1.000–1.004) | 0.041 | 1.004 (1.001–1.006) | 0.004 |
| Hypertension | 0.868 (0.600–1.255) | 0.452 | ||
| Diabetes mellitus | 1.004 (0.635–1.558) | 0.986 | ||
| CHD | 0.532 (0.247–1.145) | 0.107 | ||
| CHF | 1.154 (0.782–1.704) | 0.470 | ||
| Previous stroke | 1.354 (0.685–2.677) | 0.384 | ||
| PAD | 0.947 (0.384–2.336) | 0.905 | ||
| BNP | 1.000 (0.999–1.001) | 0.747 | ||
| eGFR | 0.988 (0.978–0.998) | 0.015 | 0.992 (0.981–1.002) | 0.106 |
| LAD | 2.624 (1.524–4.520) | 0.001 | 2.547 (1.465–4.428) | 0.001 |
| LVEF | 1.011 (0.985–1.038) | 0.416 | ||
| Antiarrhythmic drugs | 0.812 (0.478–1.381) | 0.443 | ||
| PLR | 1.462 (1.156–1.848) | 0.002 | 1.393 (1.102–1.762) | 0.006 |
| APPLE score | 1.033 (0.832–1.284) | 0.832 | ||
| CHA2DS2‑VASc score | 1.307 (0.916–1.174) | 0.567 | ||
Notes: The PLR were stratified by the tertiles of the PLR (T1, PLR ≤ 75.6; T2, 75.6 < PLR ≤ 114.9; T3, PLR> 114.9). The LAD groups were stratified by the optimal cut-off value (LAD≧42mm).
Abbreviations: AF, atrial fibrillation; BMI, body mass index; CHD, coronary heart disease; CHF, chronic heart failure; PAD, peripheral artery disease; COPD, chronic obstructive pulmonary disease; SBP, systolic blood pressure; HR, heart rate; FBG, fasting blood-glucose; BNP, brain natriuretic peptide; eGFR, Estimated glomerular filtration rate; BUA, blood uric acid; Alb, albumin; LAD, left atrial diameter; LVED, left ventricular end diastolic diameter; LVEF, left ventricular ejection fraction; PLR, platelet to lymphocyte ratio.