Table 3. ‘Alarm’ symptom-cancer pairs in the UK Biobank and CPRD comparison cohorts.
| Cancer site | Symptom | UK Biobank comparison cohort | CPRD comparison cohort | Adjusted rate ratio, UK Biobank vs CPRD | |||||
|---|---|---|---|---|---|---|---|---|---|
| Patients | (% with symptom) | Patients | (% with symptom) | ||||||
| Cancer | Symptom | Cancer | Symptom | RR | (95% CI) | ||||
| Breast | Breast lump | 2,581 | 461 | (17.9%) | 4,379 | 1,771 | (40.4%) | 0.59 | (0.54, 0.65) |
| Colorectal | Rectal bleeding | 1,238 | 144 | (11.6%) | 2,233 | 487 | (21.8%) | 0.63 | (0.53, 0.76) |
| Bladder | Haematuria | 380 | 213 | (56.1%) | 709 | 455 | (64.2%) | 1.02 | (0.91, 1.14) |
| Uterine | Post-menopausal bleeding | 335 | 117 | (34.9%) | 630 | 270 | (42.9%) | 0.84 | (0.71, 1.00) |
| Kidney | Haematuria | 272 | 53 | (19.5%) | 481 | 103 | (21.4%) | 0.79 | (0.60, 1.05) |
| Upper GI | Dysphagia | 306 | 56 | (18.3%) | 779 | 241 | (30.9%) | 0.58 | (0.44, 0.76) |