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. 2023 Dec 15;11(12):e8235. doi: 10.1002/ccr3.8235

TABLE 2.

Changes in the blood levels of caffeine and its metabolites over time.

Elapsed time from visit [h] 0 7 12 24 48 69 75
Blood concentration[μg/m L] Caffeine 384.96 245.99 87.23 55.20 7.51 1.72 1.24
Paraxanthine 6.48 15.13 11.18 8.09 2.47 0.99 0.98
Theobromine 1.32 2.55 2.37 1.49 0.56 0.29 0.30
Theophylline 0.50 1.12 0.91 0.86 0.22 0.07 0.07

Note: Blood tests performed more than 40 h after initiating CHD show that the patient's blood levels are below the toxic range for the first time.