Table 1.
Patients (n = 78) | Healthy controls (n = 130) | p | |||
---|---|---|---|---|---|
n (%) | Mdn (IQR) | n (%) | Mdn (IQR) | ||
Age (years) | 53 (15) | 53 (12) | 0.18 | ||
BMI | 23 (5) | 22 (4) | 0.40 | ||
Children (number) | 2 (2) | 2 (2) | 0.61 | ||
Smoking (yes) | 12 (15) | 15 (12) | 0.42 | ||
Menopause status* | 0.08 | ||||
Pre | 30 (39) | 56 (43) | |||
Peri | 14 (18) | 10 (8) | |||
Post | 33 (43) | 64 (49) | |||
AITD | |||||
Hashimoto’s thyroiditis | 52 (67) | ||||
Graves’ disease | 8 (10) | ||||
Not otherwise specified | 18 (23) |
Group comparisons were conducted using two-sided Mann–Whitney U tests and Pearson’s Chi-squared tests.
Mdn median, IQR interquartile range, BMI body mass index, AITD autoimmune thyroid diseases.
*Patients were categorised by self-report, whereas healthy controls were categorised by the Stages of Reproductive Aging Workshop + 10 (STRAW) criteria56: (1) pre if the menstrual cycle was regular, (2) peri if the cycle length was variable > 7 days or interval between cycles > 60 days, and (3) if there was no bleeding within 12 months.