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. 2023 Dec 16;14(12):834. doi: 10.1038/s41419-023-06350-6

Fig. 4. Peripheral monocyte/macrophage depletion protects photoreceptors after retinal detachment.

Fig. 4

A Outline of recipients, peripheral monocyte/macrophage depletion, and experimental retinal detachment model (Created with BioRender.com). B Subretinal infiltration of CD11b+ cells in control and clodronate groups after retinal detachment in retinal cryosections. C TUNEL assay in the detached retina in control and clodronate groups at day 1 after retinal detachment. D and E Representative cryosection image of TUNEL assay in control and clodronate groups at day 1 after retinal detachment. F Photoreceptor cell count in the detached retina in control and clodronate groups at day 7. Images are representative of ≥ 3 experiments (n = 4, 10). *p < 0.05. Scale bar 50 µm (D and E).