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IC50s of toxic Bmr substrates for BD170-VB cells expressing the wild-type and mutant variants of Bmr
| Strain | IC50 (μg/ml)
|
||
|---|---|---|---|
| Ethidium | Norfloxacin | Acriflavine | |
| Wild type | 12 | 1.0 | 20 |
| P347T | 25 | 2.0 | 40 |
| F143V | 3 | 0.15 | 4 |
| F143V P347S | 15 | 0.5 | 12 |
| P347S | 25 | 2.0 | 40 |
