Table 2.

CT-Derived CAD Indices in all Participants and by PCAT Density

	n/N (%)	PCAT Density, HU Median (25%–75%)	P Value
Participants with any plaque			<.001
No	371 (51.0)	−90.4 (−96.3 to −83.6)
Yes	356 (49.0)	−87.0 (−93.9 to −79.6)
Number of noncalcified segments			<.001
0 segments with noncalcified plaque	436 (60.0)	−90.1 (−95.7 to −82.5)
1–2 segments with noncalcified plaque	234 (32.2)	−87.5 (−94.1 to −80.1)
≥3 segments with noncalcified plaque	57 (7.8)	−84.0 (−90.6 to −78.9)
Stenosis			<.001
No (stenosis 0%)	371/715 (51.9)	−90.4 (−96.3 to −83.6)
Mild (stenosis 1%–49%)	319/715 (44.6)	−87.2 (−94.0 to −79.4)
Moderate (stenosis 50%–69%)	16/715 (2.2)	−83.5 (−88.9 to −79.9)
Severe (stenosis ≥70% or ≥50% left main)	9/715 (1.3)	−84.0 (−91.7 to −79.0)
CAC score			<.001
CAC = 0	452/698 (64.8)	−90.2 (−96.2 to −83.5)
CAC = 1–100	173/698 (24.8)	−85.3 (−92.9 to −78.7)
CAC = 101–400	61/698 (8.7)	−84.3 (−92.7 to −77.8)
CAC >400	12/698 (1.7)	−83.9 (−89.5 to −79.9)
Vulnerable plaque features
Any vulnerable plaque			<.001
No	563 (77.4)	−89.5 (−95.7 to −81.9)
Yes	164 (22.6)	−85.3 (−92.8 to −79.2)
Vulnerable plaque category
Positive remodeling			<.001
No	568 (78.1)	−89.4 (−95.6 to −81.9)
Yes	159 (21.9)	−85.5 (−92.9 to −79.0)
Low-attenuation plaque			.530
No	683 (94.0)	−88.9 (−95.2 to −81.1)
Yes	44 (6.1)	−86.6 (−94.2 to −82.5)
Napkin ring sign			.342
No	704 (96.8)	−88.6 (−94.8 to −81.1)
Yes	23 (3.2)	−89.6 (−98.7 to −83.9)
Leaman score			<.001
0	371/715 (51.9)	−90.4 (−96.3 to −83.6)
>0–5	230/715 (32.2)	−88.3 (−95.1 to −80.8)
>5	114/715 (15.9)	−83.9 (−90.7 to −77.9)

Leaman score reflects coronary artery disease burden based on the number of segments with plaque, plaque location, stenosis degree, and plaque morphology. P values were obtained using a nonparametric Kruskal–Wallis test.

Abbreviations: CAC, coronary artery calcium; CT, computed tomography; HU, Hounsfield unit; PCAT, pericoronary adipose tissue.