TABLE 3.

Evaluation of Direct SMA Screening test versus MLPA.

Value	Calculation	Wild type	Homozygous deletion	Results
Accuracy	(TP + TN)/(TP + TN + FP + FN)	(80 + 20)/(80 + 20 + 0 + 0)	(20 + 80)/(20 + 80 + 0 + 0)	1
Sensitivity	TP/(TP + FN)	80/(80 + 0)	20/(20 + 0)	1
Specificity	TN/(TN + FP)	20/(20 + 0)	80/(80 + 0)	1
False positive rate	FP/(TN + FP)	0/(20 + 0)	0/(80 + 0)	0
False negative rate	FN/(TP + FN)	0/(80 + 0)	0/(20 + 0)	0
Efficiency	(TP + TN)/(TP + TN + FP + FN)	(80 + 20)/(80 + 20 + 0 + 0)	(20 + 80)/(20 + 80 + 0 + 0)	1