Table 2.
Pathway analysis: altered metabolites in LNCaP-ADR vs. LNCaP parental cells using NEG mode
| Pathway name | Match status | p | -Ln(p) | Holm p | FDR | Impact |
|---|---|---|---|---|---|---|
| Arginine and proline metabolism | 12/77 | 0.000064435 | 9.6498 | 0.0051548 | 0.0051548 | 0.40538 |
| Alanine, aspartate and glutamate metabolism | 6/24 | 0.00036124 | 7.926 | 0.028538 | 0.01445 | 0.23362 |
| Pyrimidine metabolism | 9/60 | 0.00075231 | 7.1924 | 0.05868 | 0.020061 | 0.25617 |
| Taurine and hypotaurine metabolism | 5/20 | 0.0011554 | 6.7633 | 0.088965 | 0.022347 | 0.42267 |
| Purine metabolism | 11/92 | 0.0013967 | 6.5737 | 0.10615 | 0.022347 | 0.13774 |