Table 2.

The diagnostic performance of RDP signature in predicting LNM in NF-PanNETs in the training, internal and external validation cohort.

	AUC	95% CI	Accuracy	Sensitivity	Specificity	PPV	NPV	p value
Training cohort	0.89	0.83–0.94	0.77	0.82	0.73	0.73	0.82
Internal validation cohort	0.87	0.80–0.94	0.76	0.76	0.75	0.74	0.77
External validation cohort	0.91	0.85–0.97	0.87	0.91	0.79	0.97	0.82
Training cohort vs Internal validation cohort								0.75
Training cohort vs External validation cohort								0.43
Internal validation cohort vs External validation cohort								0.56

AUC, area under the curve; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.