Fig. 3.

IPES performance on EGFR genotype prediction and prognosis analysis of stage I-III resected NSCLC patients with EGFR mutation or EGFR wild-type status. (a) and (b) ROC curves represent the EGFR genotype detection performance of IPES, metadata-based model and the combined model in the (a) internal validation set and (b) external validation set. (c) and (d) Kaplan–Meier curves of the low- and high-risk subgroups predicted by IPES for stage I-III resected NSCLC patients with (c) EGFR mutation and (d) EGFR wild-type status in the internal validation set. In the Kaplan–Meier curves, the horizontal axis represents survival time (months) and the vertical axis represents survival probability.