Table 2.
Univariate and multivariate survival analysis for OS using Cox proportional hazards methods in the internal validation set.
| Univariate analysis |
Multivariate analysis |
|||
|---|---|---|---|---|
| Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
| MTL-score | 2.42 (1.78–3.29) | <0.0001 | 1.86 (1.33–2.59) | 0.00028 |
| TNM stage | 2.04 (1.53–2.72) | <0.0001 | 2.01 (1.49–2.71) | <0.0001 |
| Age | 1.06 (1.03–1.09) | <0.0001 | 1.05 (1.02–1.08) | 0.00038 |
| Sex | 1.55 (0.93–2.57) | 0.090 | 1.40 (0.68–2.90) | 0.36 |
| Smoking status | 1.12 (0.68–1.83) | 0.67 | 0.62 (0.30–1.29) | 0.20 |
| Cancer family history | 0.71 (0.26–1.95) | 0.50 | 1.17 (0.41–3.31) | 0.77 |
| Tumor family history | 1.46 (0.74–2.87) | 0.28 | 1.51 (0.75–3.05) | 0.25 |
| Histology | 1.34 (1.08–1.66) | 0.0085 | 1.26 (0.95–1.68) | 0.11 |
MTL-score = multi-task learning-based survival score. TNM = tumor-node-metastasis. CI = confidence interval.