Table IV.
Results of susceptibility testing to amikacin and clarithromycin obtained by manually conducted microdilution method. Interpretation criteria following CLSI.
| No. | Species | AN | Interpretation* | CLA after 5 days of incubation | Interpretation* | CLA after 14 days of incubation | Interpretation* |
|---|---|---|---|---|---|---|---|
| 1 | Mabs | 16 | (S) | 0.06 | (S) | 0,5 | (S) |
| 2 | Mabs | 8 | (S) | 0.06 | (S) | > 64 | (R) |
| 3 | Mabs | 16 | (S) | 0.06 | (S) | = 32 | (R) |
| 4 | Mabs | 16 | (S) | 0.06 | (S) | = 32 | (R) |
| 5 | Mabs | 16 | (S) | 0.06 | (S) | = 32 | (R) |
| 6 | Mabs | 16 | (S) | 0.06 | (S) | = 32 | (R) |
| 7 | Mmas | – | – | – | – | – | – |
| 8 | Mmas | 16 | (S) | 0.06 | (S) | = 0.125 | (S) |
| 9 | Mabs | 16 | (S) | 0.06 | (S) | = 0.125 | (S) |
| 10 | Mmas | 16 | (S) | 0.06 | (S) | = 0.06 | (S) |
| 11 | Mbol | 0.5 | (S) | 0.06 | (S) | > 64 | (R) |
| 12 | Mabs | 0.250 | (S) | 4 | (R) | = 16 | (R) |
1
Mabs – Mycobacterium abscessus subsp. Abscessus, Mmas – Mycobacterium abscessus subsp. massiliense, Mbol – Mycobacterium abscessus subsp. bolletii
1
S – susceptible, I – intermediate, R – resistant
1
AN – amikacin, CLA – clarithromycin
1
* – interpretation of the result was done according CLSI